Search for dissertations about: "Irina Radulescu"

Found 1 swedish dissertation containing the words Irina Radulescu.

2. 1. Induction and repair of DNA double-strand breaks in human cells exposed to different radiation qualities

   Author : Irina Radulescu; Karolinska Institutet; Karolinska Institutet; []
   Keywords : DSB; chromatin structure; high-LET; heat-labile sites; PFGE; DNA-PKcs; XRCC1; PARP-1; pATM; gamma-H2AX; 53BP1;

   Abstract : Radiation therapy is used in attempting to kill tumor cells by inducing DNA double- strand breaks (DSB), the most critical DNA lesions. Recent and planned radiation therapy strategies use high-linear energy transfer (LET) radiation to effectively treat malignant tumors. READ MORE