Search for dissertations about: "Ischemia reperfusion injury"

Showing result 1 - 5 of 76 swedish dissertations containing the words Ischemia reperfusion injury.

2. 1. Hepatic ischemia-reperfusion injury

   Author : Melroy Alistair D'Souza; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Hepatic ischemia-reperfusion (I/R) injury is a complex phenomenon occuring in response to interruption of the liver’s blood and oxygen supply and the subsequent restoration of blood flow and tissue oxygenation. Techniques to reduce blood loss and other intra-operative manoeuvers during liver resection can cause hepatic I/R injury. READ MORE

4. 2. Myocardial ischemia and reperfusion injury, clinical and experimental studies

   Author : Karin Åström-Olsson; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; myocardium; ischemia; reperfusion injury; FKBP12; FKBP12.6;

   Abstract : Acute myocardial infarction is the consequence of an occluded nutrient coronary artery. Reperfusion reduces infarct size and enhances the rate of survival. But reperfusion may also, in itself, cause reversible injury, stunning and arrhythmias, as well as irreversible lethal reperfusion injury. READ MORE

5. 3. Pulmonary Injury Following Intestinal Ischemia and Reperfusion in Rats

   Author : Anna Börjesson; Lund Kirurgi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reperfusion injury; intestinal ischemia; pulmonary injury; endothelium; cytokines; alveolar fluid clearance; leukocytes; orthopaedics; Surgery; traumatology; ortopedi; Kirurgi; traumatologi;

   Abstract : Intestinal ischemia and reperfusion (I/R) is a potentially life-threatening condition, sometimes leading to a systemic inflammatory response and the potential development of the multiple organ dysfunction syndrome. The overall aim of the thesis was to study the effects of intestinal I/R on pulmonary function with special emphasis on removal of excess alveolar fluid, pulmonary endothelial barrier permeability, leukocyte accumulation and function, and possible therapeutic strategies to prevent the development of pulmonary injury following intestinal I/R. READ MORE

6. 4. Renal Ischemia/Reperfusion Injury in Diabetes : Experimental Studies in the Rat

   Author : Jan Melin; Bengt Rippe; Uppsala universitet; []
   Keywords : Medical sciences; diabetes mellitus; ischemia reperfusion; rat; end-stage renal disease; inflammation; fibrosis; hyaluronan; CD44; treatment; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

   Abstract : Diabetes mellitus (DM) is one of the leading causes of end stage renal failure. An increased susceptibility to renal ischemia/reperfusion (I/R)-injury was found in DM rats. Unilateral renal ischemia for as short as 20 minutes led to an irreversible progressive injury in DM kidneys, whereas the injury in non-DM kidneys was almost reversible. READ MORE

7. 5. Intestinal ischemia and reperfusion. Proinflammatory response and organ dysfunction

   Author : Knut Olanders; Lund Institutionen för kliniska vetenskaper; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; traumatology; Kirurgi; ortopedi; traumatologi; orthopaedics; Surgery; inflammation; cytokine; leukocyte; reperfusion; ischemia; permeability; Intestine; endothelium;

   Abstract : Intestinal I/R is considered to be an important initiating event in several pathophysiological conditions such as trauma, bleeding, sepsis and pancreatitis, frequently leading to concomitant both single and potentially multiple organ dysfunction. The purpose of this thesis was to study mechanims underlying the development of multiple organ dysfunction, with special focus on intercellular proinflammatory regulation in the concurrent development of tissue injury. READ MORE