Search for dissertations about: "Islet1"

Found 4 swedish dissertations containing the word Islet1.

  2. 1. Progenitor cells in the postnatal central nervous system, characterization and genetic manipulation

    Author : Nina Rogelius; CNS Genterapi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; subventricular zone; Islet1; Neurogenin2; respecification; in vivo.; transcription factors; neurogenesis; Progenitor cells; stem cells;

    Abstract : New neurons are only generated in two places of the postnatal brain; the subventricular zone (SVZ) and hippocampus. The SVZ-derived cells specifically migrate to the olfactory bulb where they give rise to new interneurons. READ MORE

  4. 2. Heart Regeneration : Lessons from the Red Spotted Newt

    Author : Nevin Witman; Jamie Morrison; Thomas Braun; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Heart; Regeneration; Newt; microRNAs; RNA editing; Molecular Biology; molekylärbiologi;

    Abstract : Unlike mammals, adult salamanders possess an intrinsic ability to regenerate complex organs and tissue types, making them an exciting and useful model to study tissue regeneration. The aims of this thesis are two fold, (1) to develop and characterize a reproducible cardiac regeneration model system in the newt, and (2) to decipher the cellular and molecular underpinnings involved in regeneration. READ MORE

  5. 3. Directed differentiation of adult neural stem cells for cell therapy in the nervous system

    Author : Niklas Holmström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The emergence of neural stem cell research has raised hopes for cell therapy of neurological disorders. Insight into the normal mechanisms of neural stem cell fate specification and differentiation is a prerequisite for the development of safe and efficient clinical applications. READ MORE

  6. 4. Thyroid hormone mediates fibroblast growth factor receptor expression, which both alter cell surface mechanical properties of the mammalian cochlea

    Author : Katherine B Szarama; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cells in the mammalian hearing organ, the cochlea, develop a specialized patterning and cellular architecture necessary for hearing function. Cytoskeletal components, such as actin and microtubules, maintain the material and mechanical properties of these cells. READ MORE