Search for dissertations about: "Islets of Langerhans"
Showing result 21 - 25 of 107 swedish dissertations containing the words Islets of Langerhans.
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21. Studies of Innate and Adaptive Immunity in Islet Transplantation
Abstract : Clinical islet transplantation is today an established alternative treatment for a selected group of type 1 diabetes patients. The predominant technique for transplantation is infusion of islets in the liver via the portal vein. READ MORE
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22. Properties of Endothelium and its Importance in Endogenous and Transplanted Islets of Langerhans
Abstract : Transplantation of insulin producing cells is currently the only cure for type 1 diabetes. However, even though the Edmonton protocol markedly increased the success rate of pancreatic islet transplantation, the long term insulin independence is still very poor. An adequate engraftment is critical for islet graft survival and function. READ MORE
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23. On macrophage contributions to tissue homeostasis : New insights on pancreas development and healing of ischemic injury
Abstract : Besides providing host defence against innumerable threats, macrophages display additional key functions for preservation of tissue homeostasis. This thesis includes four studies that explore novel macrophage functions in both the development of islets of Langerhans and healing of ischemic injury in mice. READ MORE
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24. Studies of the Pancreas: Implications for Type 1 Diabetes Aetiology
Abstract : Type 1 diabetes (T1D) is a disease of severe insulin deficiency through loss of β cells in the endocrine pancreas. The T1D dogma maintains that a precipitating event unleashes autoimmunity in at-risk individuals, often measured through autoantibodies against β cell antigens. READ MORE
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25. Mechanisms and Therapeutic Interventions of Instant Blood-Mediated Inflammatory Reaction (IBMIR)
Abstract : Intraportal transplantation of isolated islets of Langerhans is a procedure approaching clinical acceptance as a treatment for patients with type I diabetes mellitus. One major problem with this treatment is that large amounts of cells are lost at the time of infusion into the portal vein, resulting in a low level of engraftment of the islets. READ MORE