Search for dissertations about: "Ivaylo Stoimenov"

Found 2 swedish dissertations containing the words Ivaylo Stoimenov.

  2. 1. Interplay between Transcription and Homologous Recombination in the Presence of DNA Damage

    Author : Ivaylo Stoimenov; Thomas Helleday; Niklas Schultz; Natalia Issaeva; Thierry Nouspikel; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; homologous recombination; transcription; DRB; UVC; 6-thioguanine; mammalian cells; BRCA1; BRCA2; PARP inhibitors; XP-V; Molecular biology; Molekylärbiologi; molekylärgenetik; Molecular Genetics;

    Abstract : The biochemical processes of DNA repair, replication and recombination compete for the same substrate, the DNA molecule. This competition is natural, as each process requires the same template. In order to resolve possible conflicts between these processes, when they take place on a particular stretch of DNA, certain crosstalk is expected. READ MORE

  4. 2. Prognostic and Predictive Somatic Mutations in Colorectal Cancer

    Author : Luís Nunes; Tobias Sjöblom; Bengt Glimelius; Snehangshu Kundu; Ivaylo Stoimenov; Laura DeLong Wood; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; somatic mutations; next-generation sequencing; whole-genome sequencing; transcriptomics; targeted therapy; prognosis; Medicinsk vetenskap; Medical Science;

    Abstract : Colorectal cancer (CRC) is the third most incident and the second deadliest cancer worldwide. Even though CRC incidence is strongly correlated with age, it has been increasing in developing countries and younger individuals. READ MORE