Search for dissertations about: "Jöns Hilborn"

Showing result 11 - 15 of 20 swedish dissertations containing the words Jöns Hilborn.

  2. 11. Adsorption and Ordering of Surface Active Molecules and Particles at Solid Interfaces and in the Bulk

    Author : Maja S. Hellsing; Adrian R. Rennie; Jöns Hilborn; Julia Higgins; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Physics with spec. in Atomic; Molecular and Condensed Matter Physics; Fysik med inriktning mot atom- molekyl- och kondenserande materiens fysik;

    Abstract : Factors that influence the process of adsorption and order of dilute and concentrated systems of molecules and particles are explored in this thesis.  The results are based largely on neutron scattering techniques. READ MORE

  4. 12. Bone Regeneration with Cell-free Injectable Scaffolds

    Author : Gry Hulsart Billström; Sune Larsson; Kenneth B Jonsson; Jöns Hilborn; Håkan Engqvist; Olle Svensson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bone tissue engineering; hydrogel; computed tomography; positron emission tomography; large femoral bone defect; rat model; hydrogel; in vivo; osteogenesis; bone regeneration; 3R; single-photon emission computed tomography; bone morphogenetic protein 2; calcium phosphates; injectable; bisphosphonate;

    Abstract : Bone is a remarkable multifunctional tissue with the ability to regenerate and remodel without generating any scar tissue. However, bone loss due to injury or diseases can be a great challenge and affect the patient significantly. Autologous bone grafting is commonly used throughout the world. READ MORE

  5. 13. Bone Enhancement with BMP-2 for Safe Clinical Translation

    Author : Marta Kisiel; Jöns Hilborn; Monica Wiig; Richard Oreffo; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bone repair; Bone healing; Bone morhogenetic protein-2; Osteogenesis; Extracelular matrix; Hyaluronan; Animal model; Orthopaedics; Ortopedi; Engineering Science with specialization in Materials Science; Teknisk fysik med inriktning mot materialvetenskap;

    Abstract : Bone morphogenetic protein-2 (BMP-2) is considered a promising adjuvant for the treatment of bone regeneration. However, BMP-2 delivery in a conventional collagen scaffold needs a high dose to achieve an effective outcome. Moreover, such dosage may lead to serious side effects. READ MORE

  6. 14. Evaluation of Functionalized Biopolymers as a Step Toward Targeted Therapy of Osteoporosis

    Author : Sujit Kootala; Jöns Hilborn; Peter Thomsen; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Osteoporosis; Bone regeneration; Biomaterials; Hyaluronic acid; Bisphosphonates; Osteoclasts; Osteoblasts; Growth factors; Kemi med inriktning mot polymerkemi; Chemistry with specialization in Polymer Chemistry; Kemi med inriktning mot materialkemi; Chemistry with specialization in Materials Chemistry;

    Abstract : The work presented in this thesis focuses on the development of strategies and smart bioactive materials for the treatment of osteoporosis. High and low molecular weight soluble hyaluronic acid-bisphosphonate (HA-BP) derivatives were investigated for their ability to inhibit osteoclasts. READ MORE

  7. 15. Development and optimization of a 3D in vitro model for osteogenic biomaterial evaluation

    Author : Luis Oliveros Anerillas; Peyman Kelk; Paul J. Kingham; Mikko Lammi; Jöns Hilborn; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; angiogenesis; biomaterial; bone marrow mesenchymal stem cells; bone regeneration; hydrogel; osteoinduction; osteogenesis; scaffold; type I collagen; 3D culture; biology; biologi; biomedical laboratory science; biomedicinsk laboratorievetenskap; Medical Cell Biology; medicinsk cellbiologi;

    Abstract : Despite the innate regenerative capabilities of bone tissue, self-repair is impaired when an injury exceeds the critical size threshold because of trauma, congenital, or pathological conditions. Autologous transplantation is the gold standard to reconstruct large bone defects. READ MORE