Search for dissertations about: "J. Mueller"

Found 1 swedish dissertation containing the words J. Mueller.

2. 1. Leukotriene A4 hydrolase : identification of amino acid residues involved in catalyses and substrate-mediated inactivation

   Author : Martin J Mueller; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Leukotriene (LT) A4 hydrolase catalyzes the committed step in the biosynthesis of LTB4, a classical chemoattractant and immuine-modulating lipid mediator involved in inflammation, host-defense against infections, and systemic, PAF-mediated, lethal shock. LTA4 hydrolase is a bifunctional zinc metalloenzyme with a chloride stimulated arginyl aminopeptidase activity. READ MORE