Search for dissertations about: "J3D T Iymphoma cells"

Found 1 swedish dissertation containing the words J3D T Iymphoma cells.

2. 1. The antagonistic role of activated oncogenes and apoptosis : studies of n-myc and p53 in lymphoid tumorigenesis

   Author : Yisong Wang; Karolinska Institutet; Karolinska Institutet; []
   Keywords : MPC; EmyN-myc transgene; J3D T Iymphoma cells; p53; v-m y cretrovirus; bcl-2; Gl cell cycle arrest; apoptosis; HPV 16 E7;

   Abstract : Inactivation of the p53 tumor suppressor gene and activation of proto-oncogenes have been implicated in the initiation and/or progression of a number of neoplasms. In this thesis, the involvement of N-myc gene activation has been studied in mouse plasmacytomagenesis and the role of wild-type (wt)p53 and oncogene activation has been evaluated with particular emphasis on apoptosis. READ MORE