Search for dissertations about: "Jaime M. Ross"

Found 1 swedish dissertation containing the words Jaime M. Ross.

  1. 1. Mitochondrial DNA mutations : brain developmental and ageing consequences, and possible treatments

    Author : Jaime M Ross; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Ageing is a complex process that involves cellular senescence, a gradual loss of tissue homeostasis, and decline in organ function. Abundant evidence implicates mitochondria in ageing suggesting: (i) accumulation of mitochondrial DNA (mtDNA) damage, (ii) progressive respiratory chain dysfunction, and (iii) increased reactive oxygen species production. READ MORE