Search for dissertations about: "Jan Bäckvall"
Showing result 1 - 5 of 46 swedish dissertations containing the words Jan Bäckvall.
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1. Protein engineering of enzymes for improved enantioselectivity and application of engineered enzymes in organic synthesis
Abstract : .... READ MORE
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2. Palladium(II)-Catalyzed Oxidative Carbocyclization/Functionalization of Allenynes
Abstract : The selective formation of carbon-carbon bonds constitutes a key transformation in organic synthesis with useful applications in pharmaceutical or material industry. A particularly versatile tool for carbon-carbon as well as carbon-heteroatom bond formation is palladium catalysis, which allows for mild and selective routes even towards complex structures. READ MORE
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3. Palladium(II)-Catalyzed Oxidative Carbocyclization/Functionalization of Allenynes
Abstract : Palladium catalysis has emerged as an outstanding tool in synthetic organic chemistry for the mild and selective formation of carbon-carbon and carbon-heteroatom bonds. This thesis has been directed towards the extension of palladium(II)-catalyzed carbocyclization chemistry under oxidative conditions. READ MORE
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4. Synthetic Transformations via Metal- and Enzyme-Catalyzed Dynamic Kinetic Resolution
Abstract : This thesis deals with the preparation of a new half-sandwich type ruthenium(II)- catalyst for racemization of optically active secondary alcohols and the development of a highly efficient method in combination with lipases such as Candida antarctica lipase B and Pseudomonas cepacia lipase for dynamic kinetic resolution of various functionalized alcohols under mild reaction conditions.It was shown that the RuCl(CO)2(η5-C5Ph5) complex can racemize optically active aliphatic and aromatic secondary alcohols at room temperature in rather short times. READ MORE
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5. Enantioselective Synthesis of Sec-Alcohol Derivatives and Diols via Combined Ruthenium and Enzyme Catalysis
Abstract : The first part of this thesis describes the synthesis of enantiopure secondary alcohol derivatives. These syntheses are carried out via the combination of an enzyme as a resolution catalyst and a ruthenium catalyst as a racemization catalyst, in what is called dynamic kinetic resolution (DKR). READ MORE