Search for dissertations about: "Jan Komorowski"
Showing result 16 - 20 of 20 swedish dissertations containing the words Jan Komorowski.
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16. High Confidence Network Predictions from Big Biological Data
Abstract : Biology functions in a most intriguing fashion, with human cells being regulated by multiplex networks of proteins and their dependent systems that control everything from proliferation to cell death. Notably, there are cases when these networks fail to function properly. READ MORE
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17. Genome-wide Studies of Transcriptional Regulation in Yeast
Abstract : In this thesis, nutrient signalling in yeast is used as a model to study several features of gene regulation, such as combinatorial gene regulation, the role of motif context and chromatin modifications. The nutrient signalling system in yeast consists of several pathways that transmit signals about the availability of key nutrients, and regulate the transcription of a large part of the genome. READ MORE
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18. The revolutionary partnership of computation and biology
Abstract : The organization of living beings is complex. Science uses modeling in order to gain a deeper understanding, and to be able to manipulate the processes of living organisms. To this purpose, I used and developed computational tools to investigate and model different relevant biological phenomena. READ MORE
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19. Elucidation of complex diseases by machine learning
Abstract : Uncovering the interpretability of models for complex health-related problems is a crucial task that is often neglected in machine learning (ML). The amount of available data makes the problem even more complicated. READ MORE
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20. Computational discovery of DNA methylation patterns as biomarkers of ageing, cancer, and mental disorders : Algorithms and Tools
Abstract : Epigenetics refers to the mitotically heritable modifications in gene expression without a change in the genetic code. A combination of molecular, chemical and environmental factors constituting the epigenome is involved, together with the genome, in setting up the unique functionality of each cell type. READ MORE