Search for dissertations about: "Jan W Eriksson"

Found 3 swedish dissertations containing the words Jan W Eriksson.

  1. 1. Role of nuclear receptors in the regulation of human adipose tissue metabolism

    Author : Prasad G. Kamble; Jan W Eriksson; Ingrid Dahlman; Uppsala universitet; []
    Keywords : human adipose tissue; nuclear receptors; glucocorticoids; estrogen; PPARγ; lipocalin 2; glucose uptake; lipolysis; adipogenesis; genotype-based recall;

    Abstract : Nuclear receptors modulate expression of genes involved in adipose tissue (AT) metabolism. Their improved understanding may provide new treatment options for metabolic disorders such as obesity, insulin resistance (IR) and type 2 diabetes (T2D). READ MORE

  2. 2. Insulin-antagonistic neurohormonal pathways in the development of insulin resistance and type 2 diabetes

    Author : Martin Lundqvist; Jan W Eriksson; Niclas Abrahamsson; André van Beek; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glucagon; cortisol; ACTH; growth hormone; counter-regulation; clamp; hypoglycemia; hyperglycemia; obesity; type 2 diabetes; inflammation;

    Abstract : According to the current paradigm, the development of type 2 diabetes is driven by insulin resistance and the gradual failure of beta cells to compensate for this by secreting adequate amounts of insulin. Obesity is an important risk factor for type 2 diabetes and is considered to influence disease development primarily by induction of insulin resistance, via mechanisms that have not been fully elucidated. READ MORE

  3. 3. Identifying risk of type 2 diabetes : epidemiologic perspectives from biomarkers to lifestyle

    Author : Margareta Norberg; Lars Weinehall; Jan W Eriksson; Christer Andersson; Mai-Lis Hellénius; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 diabetes mellitus; metabolic syndrome; prediction; stress; social support; smokeless tobacco; risk; obesity; lifestyle; psychosocial; clinical markers; case-referent study; cohort study; Epidemiology; Epidemiologi;

    Abstract : Type 2 diabetes is a significant health problem because of its high prevalence and strong association with cardiovascular morbidity and mortality. An increase of type 2 diabetes is predicted due to increasing obesity and sedentary lifestyle habits. READ MORE