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Showing result 1 - 5 of 41 swedish dissertations matching the above criteria.

  2. 1. Palladium(II)-Catalyzed Oxidative Carbocyclization/Functionalization of Allenynes

    Author : Teresa Bartholomeyzik; Jan-Erling Bäckvall; Diego J. Cárdenas; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; palladium catalysis; oxidation; carbocyclization; allenynes; boron reagents; kinetics; selectivity; reaction mechanism; organisk kemi; Organic Chemistry;

    Abstract : The selective formation of carbon-carbon bonds constitutes a key transformation in organic synthesis with useful applications in pharmaceutical or material industry. A particularly versatile tool for carbon-carbon as well as carbon-heteroatom bond formation is palladium catalysis, which allows for mild and selective routes even towards complex structures. READ MORE

  4. 2. Palladium(II)-Catalyzed Oxidative Carbocyclization/Functionalization of Allenynes

    Author : Teresa Bartholomeyzik; Jan-Erling Bäckvall; Antonio Bermejo-Gómez; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Palladium catalysis has emerged as an outstanding tool in synthetic organic chemistry for the mild and selective formation of carbon-carbon and carbon-heteroatom bonds. This thesis has been directed towards the extension of palladium(II)-catalyzed carbocyclization chemistry under oxidative conditions. READ MORE

  5. 3. Synthetic Transformations via Metal- and Enzyme-Catalyzed Dynamic Kinetic Resolution

    Author : Krisztián Bogár; Jan-Erling Bäckvall; Romas Kazlauskas; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; ruthenium; racemization; lipase; dynamic kinetic resolution; secondary alcohol; Candida antarctica lipase B; Organic chemistry; Organisk kemi; Organic Chemistry; organisk kemi;

    Abstract : This thesis deals with the preparation of a new half-sandwich type ruthenium(II)- catalyst for racemization of optically active secondary alcohols and the development of a highly efficient method in combination with lipases such as Candida antarctica lipase B and Pseudomonas cepacia lipase for dynamic kinetic resolution of various functionalized alcohols under mild reaction conditions.It was shown that the RuCl(CO)2(η5-C5Ph5) complex can racemize optically active aliphatic and aromatic secondary alcohols at room temperature in rather short times. READ MORE

  6. 4. Enantioselective Synthesis of Sec-Alcohol Derivatives and Diols via Combined Ruthenium and Enzyme Catalysis

    Author : Linnéa Borén; Jan-Erling Bäckvall; Romas Kazlauskas; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; catalysis; kinetic resolution; ruthenium catalyst; Dynamic kinetic resolution; Dynamic Kinetic Asymmetric Transformation; Organic chemistry; Organisk kemi; Organic Chemistry; organisk kemi;

    Abstract : The first part of this thesis describes the synthesis of enantiopure secondary alcohol derivatives. These syntheses are carried out via the combination of an enzyme as a resolution catalyst and a ruthenium catalyst as a racemization catalyst, in what is called dynamic kinetic resolution (DKR). READ MORE

  7. 5. Studies of Biomimtic Oxidations and Racemizations

    Author : Gábor Csjernyik; Jan-Erling Bäckvall; Serafino Gladiali; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; oxidation of alcohols; ruthenium; porphyrin; racemization;

    Abstract : This thesis deals with studies of ruthenium-catalyzed hydrogen transfer reactions for oxidations and racemization.Through optimisation of the substrate-selective redox catalyst, the electron and proton transfer mediator (a benzoquinone derivative), and the oxygen-activating metal macrocycle a highly efficient biomimetic oxidation of secondary alcohols was obtained. READ MORE