Search for dissertations about: "Javier Augusto Sánchez Saavedra"

Found 1 swedish dissertation containing the words Javier Augusto Sánchez Saavedra.

2. 1. Inhibition of the plasma contact system on endpoint immobilized heparin and human endothelium

   Author : Javier Augusto Sánchez Saavedra; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Contact activation system; FXII; prokallikrein; antithrombin; specific AT-binding site; immobilized heparin; heparan sulphate; endothelium;

   Abstract : When blood is exposed to foreign materials or injured tissue, several defense systems are activated. The contact with an artificial surface leads to activation of FXII, the first proenzyme of the plasma contact activation system, with concomitant triggering of the intrinsic coagulation and also the fibrinolytic-, kallikrein- and complement systems. READ MORE