Search for dissertations about: "Jeanette Leusen"

Found 1 swedish dissertation containing the words Jeanette Leusen.

2. 1. The Role of Fc gamma Receptors and Mast Cell Chymase in Autoimmune Arthritis

   Author : Sofia Magnusson; Sandra Kleinau; Jeanette Leusen; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; fc gamma receptors; rheumatoid arthritis; antibodies; mast cells; mast cell; Immunology; Immunologi; Immunologi; Immunology;

   Abstract : In autoimmune diseases such as rheumatoid arthritis (RA), self-reactive antibodies are present at high levels, which contributes to disease pathogenesis. The antibodies mediate their effect predominantly by binding to Fc gamma receptors (FcγR) on various leukocytes, such as monocytes, macrophages and mast cells, where FcγR ligation leads to cell activation. READ MORE