Search for dissertations about: "Jennie Georgsson"

Found 1 swedish dissertation containing the words Jennie Georgsson.

2. 1. Design and Synthesis of Novel AT2 Receptor Ligands : From Peptides to Drug-Like Molecules

   Author : Jennie Georgsson; Anders Hallberg; Kevin Burgess; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; angiotensin II; AT1; AT2; AT2 receptor agonist; peptidomimetics; γ-turn mimetics; carbonylation; microwave; molybdenum hexacarbonyl; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi;

   Abstract : Many peptide receptors are of pharmaceutical interest and there is thus a need for new ligands for such receptors. Unfortunately, peptides are not suitable as orally administrated drugs since they are associated with poor absorption, rapid metabolism and low sub-receptor selectivity. READ MORE