Search for dissertations about: "Jharna Barman"

Found 1 swedish dissertation containing the words Jharna Barman.

2. 1. Targeting RNA by the Antisense Approach and a Close Look at RNA Cleavage Reaction

   Author : Jharna Barman; Lars Baltzer; Roger Strömberg; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; mRNA targeting; antisense oligonucleotides; target affinity; RNase H; Michaelis-Menten kinetics; exo-nuclease stability; NMR; pH titration; alkaline hydrolysis; Organisk kemi;

   Abstract : This thesis summarizes the results of studies on two aspects of nucleic acids. Chemically modified antisense oligonucleotides (AONs) have been evaluated with regards to their suitability for mRNA targeting in an antisense approach (Paper I – III). READ MORE