Search for dissertations about: "Jin Jin"

Showing result 1 - 5 of 67 swedish dissertations containing the words Jin Jin.

  2. 1. Pharmacometric Models for Antibody Drug Conjugates and Taxanes in HER2+ and HER2- Breast Cancer

    Author : Brendan Bender; Lena Friberg; Mats Karlsson; Jin Jin; Oscar della Pasqua; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacometric; PKPD; model; breast cancer; T-DM1; thrombocytopenia; hepatotoxiticy; HER2; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

    Abstract : In oncology, there is a need to optimize drug treatment for efficient eradication of tumors, minimization of adverse effects (AEs), and prolonging patient survival. Pharmacometric models can be developed to streamline information between drug development phases, describe and quantify response to treatment, and determine dose regimens that balance toxicity and efficacy. READ MORE

  4. 2. Influence of Fluid Shear on Primary  Nucleation of Organic Compounds in Solution  Jin Liu  Doctoral Thesis

    Author : Jin Liu; Åke Rasmuson; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Agitation; Primary nucleation; Induction time; Fluid shear; Energy dissipation; Mass transfer; Molecular alignment; Cluster coalescence; Butyl paraben; Curcumin; m-Hydroxybenzoic acid; Solid-liquid interfacial energy; Nuclei critical radius.; Chemical Engineering; Kemiteknik;

    Abstract : In this work, three experimental systems have been used to study the influence of agitation/ fluid shear on primary nucleation. Three organic compounds have been used with different solvents, i.e. butyl paraben in ethanol solution, curcumin in ethanol solution and m-hydroxybenzoic acid in 1-propanol solution. READ MORE

  5. 3. Regulation of dendritic cell differentiation, maturation and activation

    Author : Jin Hu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The human immune system efficiently protects the host from exogenous pathogens such as bacteria, virus and parasites and endogenous threats such as damaged cells and tumors. Invasion of pathogens and other threats activate the innate immunity causing secretion of pro-inflammatory cytokines with the subsequent antigen presentation and activation of the adaptive immunity resulting in T and B cell responses. READ MORE

  6. 4. Sequential Data Learning, Scalable Models and Adversarial Regularization

    Author : Jin Huang; Ming Xiao; Geyong Min; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Abstract : Time Series Prediction (TSP) has been used in mobile network traffic data analysis to produce predictive results for network planning and resource allocation. In the first part of this thesis, we propose a novel method of predicting mobile network traffic using neural networks based on conditional probability modeling between adjacent data windows in the time series sequence. READ MORE

  7. 5. Symplectic Embeddings and results in TDA

    Author : Alvin Jin; Wojciech Chacholski; Gregory Arone; Henry Adams; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Matematik; Mathematics;

    Abstract : This thesis is a collection of work under the theme of “applied topology."  The linking idea behind seemingly disjoint fields is the existence of a filtration that one uses to study a space. In turn, given the ubiquitous nature of filtrations, applications range from theoretical fields (e.g. READ MORE