Search for dissertations about: "Joachim Lundahl"

Found 5 swedish dissertations containing the words Joachim Lundahl.

  1. 1. T Cells and NK Cells in Coronary Artery Disease : Longitudinal and methodological studies in humans

    Author : Karin Backteman; Jan Ernerudh; Lena Jonasson; Joachim Lundahl; Linköpings universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Coronary artery disease (CAD) is the leading cause of death worldwide and most often due to atherosclerosis. Atherosclerosis is a chronic inflammatory process that involves the arteries, inclouding those that supply blood to the heart muscle. READ MORE

  2. 2. Migration on extracellular matrix surface and infiltration into matrix - two distinguishable activities of human T cells

    Author : Jyrki Ivanoff; Karl-Gösta Sundqvist; Joachim Lundahl; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; extracellular matrix; fibronectin; collagen type IV; laminin; neuropeptide; chemokine; TIMP-1; MMP-9; T cells; Migration; Immunologi; Immunology; Immunologi; Clinical Immunology; klinisk immunologi;

    Abstract : Migration of T-lymphocytes on a surface coated with extracellular matrix (ECM) components (two-dimensional (2-D) migration) and migration (infiltration) into a matrix (Three-dimesional (3-D) migration) are complex events and the underlying mechanisms are not yet fully understood. Here 2-D and 3-D migration were studied by use of seven leukemic T-cell lines representing discrete differentiation stages, a non-leukemic T-cell clone, and normal peripheral blood T cells. READ MORE

  3. 3. Eosinophil Apoptosis

    Author : Kristina Seton; Joachim Lundahl; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Cell biology; Apoptosis; Programmed Cell Death; Survival; Eosinophils; Inflammatory Diseases; Resolution of inflammation; Functions; Flow cytometry; Cellbiologi; Cell biology; Cellbiologi; Clinical Chemistry; klinisk kemi;

    Abstract : Apoptosis or programmed cell death is crucial for the resolution of inflammation, and phagocytosis of apoptotic cells initiates the release of actively anti-inflammatory responses from the phagocytes. Eosinophils are one of the most potent inflammatory cells in the body and is involved in a number of diseases, most commonly associated with parasitic infections and allergic diseases. READ MORE

  4. 4. Granulocyte Adhesion to Matrix Proteins and the Effect on the Release of Granule Proteins : Development of a Simple Method and its Application in Experimental and Clinical Studies

    Author : Xiaoyan Xu; Joachim Lundahl; Uppsala universitet; []
    Keywords : Medical sciences; Eosinophils; Neutrophils; Adhesion; Release of ECP; Extracellular matrix proteins; Granulocytes; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Clinical Chemistry; klinisk kemi;

    Abstract : Granulocyte adhesion and release of their granule proteins are key steps during selective accumulation of a certain cell to an inflammatory site. Eosinophils are specifically recruited to sites of allergic inflammation and parasitic infection, whereas neutrophil influx predominates in bacterial infection and rheumatoid arthritis. READ MORE

  5. 5. Functional Role of Immune Complexes in Rheumatic and Parasitic Diseases

    Author : Erik Åhlin; Johan Rönnelid; Karlis Pauksens; Bo Nilsson; Joachim Lundahl; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical immunology; Klinisk immunologi; Medical Science; Medicinsk vetenskap;

    Abstract : Immune complexes (IC) have key pathological roles in both autoimmune and infectious diseases. In this thesis functional mechanisms behind IC-driven inflammation in rheumatic diseases and tropical infections have been studied, with special focus on the contribution of autoantibodies and cytokine-inducing properties of IC. READ MORE