Search for dissertations about: "Joakim Lundeberg"
Showing result 16 - 20 of 41 swedish dissertations containing the words Joakim Lundeberg.
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16. Library Preparation for High Throughput DNA Sequencing
Abstract : Order 3 billion base pairs of DNA in the correct order and you get the blueprint of a human, the genome. Before the introduction of massively parallel sequencing a little more than a decade ago it would cost around $10 million to get this blueprint. READ MORE
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17. On Transcriptome Sequencing
Abstract : This thesis is about the use of massive DNA sequencing to investigate the transcriptome. During recent decades, several studies have made it clear that the transcriptome comprises a more complex set of biochemical machinery than was previously believed. READ MORE
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18. The Spatial Context – through the lens of method development
Abstract : In the present moment of time, we find ourselves in a period where the advancement of genomic tools is progressing at a fast pace. Of particular interest for this thesis is the study of gene activity. READ MORE
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19. Arrayed identification of DNA signatures
Abstract : In this thesis techniques are presented that aim to determine individual DNA signatures by controlled synthesis of nucleic acid multimers. Allele-specific extension reactions with an improved specificity were applied for several genomic purposes. Since DNA polymerases extend some mismatched 3’-end primers, an improved specificity is a concern. READ MORE
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20. Mapping Transcriptomes in Tissues
Abstract : Over the past few decades, the advent of pioneering biotechnological methods has allowed scientists to analyze the molecular components of multicellular organisms with remarkable precision. The field of transcriptomics has witnessed a rapid development of technologies for gene expression profiling of biological samples. READ MORE