Search for dissertations about: "Johan D Söderholm"

Showing result 1 - 5 of 13 swedish dissertations containing the words Johan D Söderholm.

2. 1. Cancer and reconstructive surgery in Inflammatory bowel disease

   Author : Maie Abdalla; Pär Myrelid; Johan D Söderholm; Roland Andersson; Kalle Landerholm; Yves Panis; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inflammatory bowel disease; Colorectal cancer; IRA; IPAA; Primary sclerosing cholangitis;

   Abstract : Ulcerative colitis (UC) is a chronic inflammatory disease that affects the colon. According to the literature, some thirty percent of UC patients may require a subtotal colectomy and ileostomy due to failure of medical treatment, acute toxic colitis or dysplasia/cancer diagnosis. READ MORE

4. 2. Role of mast cells and probiotics in the regulation of intestinal barrier function

   Author : Anders Carlsson; Johan D. Söderholm; Åsa Keita; Karl-Eric Magnusson; Björn Weström; Linköpings universitet; []
   Keywords : ;

   Abstract : The intestinal mucosa is the largest contact area and one of the most important barriers to the outside environment. It is highly specialized in aiding us digest and absorb nutrients. It is daily exposed to several potentially dangerous substances and microorganisms, which if they were allowed to pass into the body, could give rise to diseases. READ MORE

5. 3. Neuro-immuno-regulation of inflammation in the colonic mucosa : Focus on mast cells and eosinophils in bowel disorders

   Author : Maria Teresa Casado Bedmar; Åsa Keita; Johan D Söderholm; Marie Carlson; Melanie Gareau; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mast cells; Eosinophils; Vasoactive intestinal polypeptide; Neuro-immune; Intestinal barrier; Irritable bowel syndrome; Inflammatory bowel diseases; Ussing chamber; Advance image analysis;

   Abstract : Intestinal homeostasis is key to control uptake across the mucosa and protect from harmful substances. Disturbances in the bidirectional communication between the gut and the brain are implicated in irritable bowel syndrome (IBS) and inflammatory bowel diseases (IBD), being Crohn’s disease (CD) and ulcerative colitis (UC) the two most common IBD subtypes. READ MORE

6. 4. Effects of Complement Opsonization of HIV on Dendritic Cells : and Implications for the Immune Response

   Author : Rada Ellegård; Marie Larsson; Jorma Hinkula; Johan D Söderholm; William Paxton; Linköpings universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; HIV; dendritic cells; complement; innate immune response; TLR signaling; T cell activation; NK cells; inflammation; antiviral response; immune evasion;

   Abstract : Dendritic cells are key players during HIV pathogenesis, and shape both the immediate immune response at the site of infection as well as directing the adaptive immune response against the virus. HIV has developed a plethora of immune evasion mechanisms that hijack dendritic cell functions, suppressing their ability to mount an accurate immune response and exploiting them for efficient viral transfer to target T cells. READ MORE

7. 5. The neuronal and non-neuronal substance P, VIP and cholinergic systems in the colon in ulcerative colitis

   Author : Maria Jönsson; Sture Forsgren; Örjan Norrgård; Johan D Söderholm; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ulcerative colitis; neuropeptides; substance P; VIP; non-neuronal cholinergic system; Anatomy; Anatomi; Surgery; Kirurgi; anatomi; Human Anatomy;

   Abstract : Ulcerative colitis (UC) is a chronic relapsing inflammatory bowel disease. Neuropeptides, especially vasoactive intestinal peptide (VIP) and substance P (SP), have long been considered to play key roles in UC. Among other effects, these neuropeptides have trophic and growth-modulating as well as wound-healing effects. READ MORE