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Showing result 1 - 5 of 13 swedish dissertations matching the above criteria.

  2. 1. Development of lentiviral vectors for CNS gene transfer

    Author : Johan Jakobsson; Brain Repair and Imaging in Neural Systems (BRAINS); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; Biotechnology; Gene Therapy; Neurological disorders;

    Abstract : Gene therapy in the brain is a promising treatment strategy that in the future may be used for several brain disorders, including Parkinson's disease, Alzheimer's disease and lysosomal storage diseases. By introducing a new gene, rather than providing a classical pharmacological drug, gene therapy offers the opportunity to treat neurological disorders by a single intervention. READ MORE

  4. 2. The industrial exporter-distributor trade relationship - A portrayal of the development path derived from diverging agendas

    Author : Johan Jakobsson; Göteborgs universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Exporter; Distributor; relationship; Deterioration;

    Abstract : .... READ MORE

  5. 3. Unfolding Evolutionary Growth Within a Subsidiary: The Case of a Sales Subsidiary in the Middle East

    Author : Johan Jakobsson; Göteborgs universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Evolutionary Growth; Capabilities; Multinational Corporation; Resource Management; Subsidiary; Subsidiary Charter; Subsidiary Evolution;

    Abstract : Subsidiaries are important entities in multinational corporations and are typically established with predetermined business responsibilities. A subsidiary responds to actors in the internal network (e.g. , HQs and other subsidiaries) as well as actors in the external network (e. READ MORE

  6. 4. Modulation of Angiogenesis by Laminins and Heparan Sulfate

    Author : Lars Jakobsson; Lena Claesson-Welsh; Johan Kreuger; Elisabetta Dejana; Uppsala universitet; []
    Keywords : Molecular medicine; Embryonic stem; heparan sulfate; laminin; basement membrane; VEGFR-2; VEGF; endothelial cell; signaling; angiogenesis; vasculogenesis; embryoid body; Molekylärmedicin;

    Abstract : Blood vessels transport blood with essential nutrients and oxygen to the cells in our body. In a healthy adult, formation of new vessels (angiogenesis) occurs only in case of tissue repair and growth. READ MORE

  7. 5. Cell type-specific translatome analysis of mouse models of three genetic neurodegenerative diseases

    Author : Susanne Bauer; Walker Scott Jackson; Martin Hallbeck; Per Hammarström; Johan Jakobsson; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The burden neurodegenerative diseases place on patients, their loved ones, and the healthcare system is significant, and despite extensive research efforts, there is currently no cure. Since degenerative changes in the brain can begin years before symptoms appear, early intervention is critical. READ MORE