Search for dissertations about: "Johan Jarmander"

Found 2 swedish dissertations containing the words Johan Jarmander.

  1. 1. Strategies for improved Escherichia coli bioprocessing performance

    Author : Johan Jarmander; Gen Larsson; Thomas Egli; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; E. coli; Salmonella; surface expression; autotransport; AIDA-I; lignocellulose; glucose; xylose; arabinose; simultaneous uptake; 3HB; Bioteknologi; Biotechnology;

    Abstract : Escherichia coli has a proven track record for successful production of anything from small molecules like organic acids to large therapeutic proteins, and has thus important applications in both R&D and commercial production. The versatility of this organism in combination with the accumulated knowledge of its genome, metabolism and physiology, has allowed for development of specialty strains capable of performing very specific tasks, opening up opportunities within new areas. READ MORE

  2. 2. Improved detection and performance of surface expression from the AIDA-I autotransporter

    Author : Johan Jarmander; Gen Larsson; Ulrika Rova; Ines Ezcurra; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; surface expression; autotransport; AIDA-I; Escherichia coli; proteolysis; detection tag;

    Abstract : Surface expression of recombinant proteins has attracted a lot of attention due to its potential in applications such as enzyme production, vaccine delivery and bioremediation. Autotransporters have been used for surface expression of a variety of proteins, but the expression systems reported in literature have typically been inflexible and incapable of detecting proteolysis, thereby limiting surface expression yield. READ MORE