Search for dissertations about: "Johan Lengqvist"

Found 2 swedish dissertations containing the words Johan Lengqvist.

  2. 1. Native protein mass spectrometry of nuclear receptor-ligand and enzyme-substrate complexes

    Author : Johan Lengqvist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Mass spectrometry; electrospray; nuclear receptor; retinoid X receptor; fatty acid; membrane protein; glutathione transferase; glutathione;

    Abstract : Nuclear receptors (NRs) are transcription factors that are activated by the binding of low molecular weight ligands. The NR superfamily includes receptors for steroid hormones, anti-inflammatory and lipid-lowering drugs as well as endogenous compounds such as bile acids and fatty acids. READ MORE

  4. 2. Towards an Earlier Detection of Progressive Multiple Sclerosis using Metabolomics and Machine Learning

    Author : Stephanie Herman; Kim Kultima; Ola Spjuth; Joachim Burman; Johan Lengqvist; Camilla Svensson; Gabi Kastenmüller; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bioinformatics; biomarkers; progressive multiple sclerosis; metabolomics; machine learning; advanced analytics; mass spectrometry;

    Abstract : Decision-making guided by advanced analytics is becoming increasingly common in many fields. Implementing computationally driven healthcare solutions does, however, pose ethical dilemmas as it involves human health. READ MORE