Search for dissertations about: "Johanna Haglund"

Found 4 swedish dissertations containing the words Johanna Haglund.

  2. 1. Supernucleophilic Cob(I)alamin : analytical tool for genotoxic compounds in vitro and in vivo

    Author : Johanna Haglund; Eddy Esmans; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; toxikologisk genetik; Genetic Toxicology;

    Abstract : The low but still non-acceptable levels of exposure to genotoxic compounds emphasises the need for sensitive methods for searching, detecting, identifying and quantifying these compounds. Within the field of studies on genotoxic compounds, chemically quantitative work is required throughout. READ MORE

  4. 2. New methods for determination of airborne pollutants : Focus on tetrabromobisphenol A, organophosphate triesters and polycyclic aromatic hydrocarbons

    Author : Johanna Tollbäck; Ulrika Nilsson; Peter Haglund; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Air sampling; sampling methods; indoor air; SPE; SPME; extraction; dynamic extraction; online coupling; SWE; subcritical water extraction; GC MS; LC MS; organophosphate triesters; PAH; tetrabromobisphenol A; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Abstract : The work presented in this thesis concerns the development and evaluation of new methods of sampling and analysis of organic pollutants in the indoor and outdoor environment. In Paper I, the development of a new method was reported for the determination of the brominated flame retardant tetrabromobisphenol A (TBBPA) in air using sampling with glass fiber filter and polyurethane foam (PUF), ultrasonic solvent extraction and liquid chromatography coupled to electrospray ionisation mass spectrometry (LC-ESI/MS). READ MORE

  5. 3. Inflammatory Reactions in Peritonitis and Malignant Obstructive Jaundice : Clinical and Experimental Studies with Special Emphasis on the Cellular Immune Response

    Author : Johanna Österberg; Ulf Haglund; Mikael Ljungdahl; Roland Andersson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; CLP; sepsis; peritonitis; bacterial translocation; malignant obstructive jaundice; Linomide; COX inhibitor; SC-236; indometacin; T lymphocyte; macrophage; mucosa; MLN; gut immune cell distribution; mucosal injury; cytokines; TNF-α; IL-6; IL-10; endotoxin; caspase-3; apoptosis; Kirurgi; Surgery; Kirurgi;

    Abstract : Patients with peritonitis or malignant obstructive jaundice (HPB+) have an increased morbidity and mortality due to sepsis. An altered cell-mediated immunity in the intestinal mucosa might promote gut barrier failure, increased endotoxin and cytokine release and bacterial translocation (BT) in these conditions. READ MORE

  6. 4. Cob(I)alamin as a Quantitative Tool for Analysis, Metabolism and Toxicological Studies of Electrophilic Compounds : Butadiene Epoxides, Glycidamide and Sucralose

    Author : Hitesh Vijay Motwani; Margareta Törnqvist; Bernard T Golding; Johanna Haglund; Wolfgang Buckel; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Environmental chemistry; Miljökemi; Environmental Chemistry; miljökemi;

    Abstract : Vitamin B12 can be reduced to cob(I)alamin [Cbl(I)], which is one of the most powerful nucleophiles known and referred to as a “supernucleophile”. Cbl(I) was applied as a tool in toxicological studies of the air pollutant 1,3-butadiene (BD), the toxicant acrylamide (AA) present in many foods, and the artificial sweetener sucralose. READ MORE