Search for dissertations about: "Johanna Wanngren"

Found 1 swedish dissertation containing the words Johanna Wanngren.

  1. 1. Molecular studies of the γ-secretase complex : focus on genetic and pharmacological modulation

    Author : Johanna Wanngren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : γ-Secretase is a multi-subunit protease complex, composed of presenilin (PS1 or PS2), Nicastrin, Pen-2 and Aph-1, which generates the Alzheimer disease (AD) related 30-43 amino acid long amyloid β-peptide (Aβ). The complex is also crucial for important cell signaling, such as the Notch receptor pathway. READ MORE