Search for dissertations about: "Johannes G. de Vries"

Found 1 swedish dissertation containing the words Johannes G. de Vries.

2. 1. Transition metal- and lipase-catalyzed reactions : Dynamic resolutions, hydrogen transfer and enzyme engineering

   Author : Patrik Krumlinde; Jan-Erling Bäckvall; Johannes G. de Vries; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Dynamic kinetic resolution; dynamic kinetic asymmetric transformation; hydrogen transfer; directed evolution; enzyme engineering; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

   Abstract : This thesis mainly focuses on chemoenzymatic processes and can be divided into three parts: The first part of the thesis, chapters 2-4, is devoted to the development of combined ruthenium- and enzyme-catalyzed dynamic processes. In these processes the metal catalyst racemizes (epimerizes) the alcohol substrate via hydrogen transfer and the enzyme transforms the substrate into enantiomerically enriched product. READ MORE