Search for dissertations about: "John Gribben"

Found 1 swedish dissertation containing the words John Gribben.

2. 1. Molecular and Genetic Evidence for Antigen Selection in the Pathogenesis of Chronic Lymphocytic Leukemia

   Author : Lesley Ann Sutton; Richard Rosenquist; John Gribben; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IGHV4-34; microenvironment; stereotypy; immunoglobulin; intraclonal diversification; clonal evolution;

   Abstract : Antigens play a critical role in the development of chronic lymphocytic leukemia (CLL) by binding to and stimulating leukemic precursor cells at some point during CLL ontogeny. Nevertheless, much remains unknown and further studies are necessary before an accurate model of antigen-drive can be ascertained. READ MORE