Search for dissertations about: "John P. Giesy"
Found 1 swedish dissertation containing the words John P. Giesy.
1. Bioassay analysis of dioxin-like compounds : response interactions and environmental transformation of Ah receptor agonists
Abstract : Dioxin-like compounds mediate their toxicity by binding to the aryl hydrocarbon receptor (AhR) and through this receptor a cascade of biochemical and toxic events are triggered. Mechanism-specific dioxin bioassays utilise the AhR coupled induction of endogenous CYP1A proteins or reporter gene systems for detection of dioxin-like compounds and other AhR ligands. READ MORE