Search for dissertations about: "Jonas Wetterö"

Showing result 1 - 5 of 8 swedish dissertations containing the words Jonas Wetterö.

  1. 1. Acute inflammation on model biomaterial surfaces : studies on proteins, neutrophils and platelets

    Author : Jonas Wetterö; Ulf Sjöbring; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Although most biomedical devices are non-toxic, disturbed acute and chronic inflammation and the lack of integration in tissues is a concern. At the time of biomaterial insertion, protein adsorption onto material surfaces precedes cell adhesion and is believed to alter unfavorably the acute inflammatory response and the subsequent tissue healing. READ MORE

  2. 2. Biomarkers and mediators in systemic lupus erythematosus : IFNα versus the CRP response, and evaluation of suPAR and anti-dsDNA antibody assays

    Author : Helena Enocsson; Jonas Wetterö; Thomas Skogh; Christopher Sjöwall; Søren Jacobsen; Linköpings universitet; []
    Keywords : ;

    Abstract : Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease which may affect multiple organ systems. Interferon alpha (IFNα) and autoantibodies that form immune complexes with nuclear antigens (ANA) are hallmarks believed to drive the disease into a vicious circle of inflammation, tissue damage, autoantigen exposure and autoantibody production. READ MORE

  3. 3. Antinuclear and antiphospholipid antibodies versus disease manifestations and clinical outcomes in systemic lupus erythematosus

    Author : Martina Frodlund; Christopher Sjöwall; Jonas Wetterö; Thomas Skogh; Lene Dreyer; Linköpings universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Systemic lupus erythematosus (SLE) has an exceptionally heterogeneous clinical spectrum, ranging from mild disease limited to skin and joints to severe manifestations with renal disorder, central nervous system disease, severe cytopenias and thromboembolic events. Important clinical challenges include the prediction of disease flares and the identification of individuals that are likely to evolve severe disease with accrual of organ damage and worse prognosis. READ MORE

  4. 4. Aquaporins in Infection and Inflammation

    Author : Angelika Holm; Elena Vikström; Karl-Eric Magnusson; Vesa Loitto; Jonas Wetterö; Mikael Rhen; Linköpings universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES;

    Abstract : The ability of eukaryotic cells to change their shape and to migrate directionally is highly dependent on active volume regulation in cells building up tissues as well as in individual cells. Transmembrane fluxes of water via specialized water channels, called aquaporins (AQPs), facilitate the changes of volume and shape, which additionally require a complex interplay between the plasma membrane and the cytoskeleton. READ MORE

  5. 5. Structure and Interactions of Human IgG-Fc

    Author : Daniel Kanmert; Karin Enander; Thomas Skogh; Jonas Wetterö; Sara Snogerup; Linköpings universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : This thesis involves structure and interaction studies of the Fc fragment of human IgG. For this purpose, hIgG-Fc of different subclasses were cloned and expressed in the eukaryotic host Pichia pastoris, where relevant protein modification at the post-translational level can be obtained. READ MORE