Search for dissertations about: "Josep Casadesús"
Found 3 swedish dissertations containing the words Josep Casadesús.
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1. Mechanisms and Dynamics of Carbapenem Resistance in Escherichia coli
Abstract : The emergence of extended spectrum β-lactamase (ESBL) producing Enterobacteriaceae worldwide has led to an increased use of carbapenems and may drive the development of carbapenem resistance. Existing mechanisms are mainly due to acquired carbapenemases or the combination of ESBL-production and reduced outer membrane permeability. READ MORE
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2. Evolution of Antibiotic Resistance
Abstract : The emergence of antimicrobial resistance is a major global threat to modern medicine. The rapid dissemination of resistant pathogens and the associated loss of efficacy of many important drugs needs to be met with the development of new antibiotics and alternative treatment options. READ MORE
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3. Dynamics and Mechanisms of Adaptive Evolution in Bacteria
Abstract : Determining the properties of mutations is fundamental to understanding the mechanisms of adaptive evolution. The major goal of this thesis is to investigate the mechanisms of bacterial adaptation to new environments using experimental evolution. READ MORE