Search for dissertations about: "Jun Gu"

Showing result 1 - 5 of 9 swedish dissertations containing the words Jun Gu.

  2. 1. Impulse noise and brain injury. An experimental study in rats

    Author : Annette Säljö Moberg; Göteborgs universitet; []
    Keywords : apoptosis; astrocytes; brain injury; blast; c-Fos; c-Jun; c-Myc; impulse noise; ; neurons; neurofilament; NSE; rat and S-100;

    Abstract : Abstract. Pressure waves, experienced as impulse noise, affect many body organs, although most attention has been paid to the inner ear. Impulse noise is produced by e.g. READ MORE

  4. 2. Regulation of vascular function by fluid mechanical forces. Development of a new vascular experimental platform for integrative physiological and molecular biological studies of living conduit vessels

    Author : Li-Ming Gan; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; perfusion model; endothelium; smooth muscle cells; shear stress; pressure; nitric oxide; endothelin-1; vascular endothelial growth factor; c-jun; c-fos; real-time PCR; NO probe.;

    Abstract : The vascular endothelium is a multifunctional interface between blood flow and target organs and is continuously exposed to fluid mechanical forces such as shear stress, compressive, and tensile forces. Both in vivo and in vitro data indicate that biomechanical forces exert important modulating effects on key vascular functions. READ MORE

  5. 3. Assessment of experimental neurotrauma

    Author : Ying-Lai Huang; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Impulse noise; diffuse brain injury; focal brain injury; closed head injury; NSE; S-100; GFAP; apoptosis; astrocytosis; glutamate; c-JUN; rotational acceleration; CSF;

    Abstract : Model systems of closed head injury are designed to replicate aspects of traumatic brain injury, ischemia and epilepsy in man. The aim of this thesis was to (1) develop sensitive systems enabling analyses of the biochemical reactions, as reflected by leakage of marker compounds to the cerebrospinal fluid (CSF); and (2) develop and assess a new model for closed head injury and associated dynamic changes in the brain cell. READ MORE

  6. 4. Transcriptional regulation of the latent membrane protein 1 gene by Epstein-Barr virus nuclear antigen 2

    Author : Lars Palmqvist; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epstein-Barr virus; B-cell; transformation; LMP1; EBNA2; transcription; phosphorylation; histone acetylation;

    Abstract : The Epstein-Barr virus (EBV) is a ubiquitous human herpes virus, which infects B-cells. This leads to a life-long latent infection, which in most cases is non-pathogenic. However, EBV is etiologically associated with several human malignancies, including endemic Burkitt's lymphoma, nasopharyngeal carcinoma and post-transplant lymphoma. READ MORE

  7. 5. Apoptotic mechanisms in the neonatal brain following hypoxia-ischemia

    Author : Ylva Carlsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hypoxia-ischemia brain caspase-2 cyclophilin D MLK neonatal.;

    Abstract : Neonatal encephalopathy is often perinatally acquired and caused by hypoxia-ischemia (HI). Brain injury develops with a delay, over 12-48 hours, after the insult. Hypothermia, an established neuroprotective treatment, saves 1 infant in 9 from neurological deficits suggesting that there is room for further improvement. READ MORE