Search for dissertations about: "Kärlfysiologi"

Showing result 1 - 5 of 10 swedish dissertations containing the word Kärlfysiologi.

  2. 1. Mechanosensing in the vascular wall - the role of cellular microdomains in vascular remodeling

    Author : Sebastian Albinsson; Kärlfysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; tissue culture; Histologi; cytokemi; histokemi; vävnadskultur; cytochemistry; histochemistry; wall stress; shear stress; hypertension; Histology; differentiation; growth; caveolin; smooth muscle; actin; Fysiologi; Cardiovascular system; Kardiovaskulära systemet;

    Abstract : The vascular wall has a remarkable capacity to adapt to mechanical forces exerted by the intraluminal blood pressure and flow. This includes rapid change in contractile tone as well as chronic alteration of vessel structure if the stimulus persists. Stretch of the intact blood vessel wall promotes growth and contractile differentiation. READ MORE

  4. 2. Ion channels and electrical activity in vascular smooth muscle: Effects of calcium store depletion, cholesterol and cholesterol-lowering drugs

    Author : Andreas Bergdahl; Kärlfysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fysiologi; Physiology; statins; endothelin; cholesterol; caveolae; smooth muscle; TRP; Ca2 channels; SOC;

    Abstract : Smooth muscle cells (SMCs) in the vessel wall contract to regulate blood flow and pressure, a function essential for normal circulation through tissues. On the other hand, migration and proliferation of SMCs are important factors in vascular disease, such as atherosclerosis and restenosis following surgical dilatation. READ MORE

  5. 3. Regulation of the myogenic response and stretch-induced calcium signaling in the vascular wall: Novel insights into the role of microRNAs and protein tyrosine kinase 2

    Author : Anirban Bhattachariya; Kärlfysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; portal vein; resistance artery; myogenic tone; PYK2; calcium; microRNA;

    Abstract : Intraluminal pressure has a significant impact on vascular adaptability, phenotype and regulation of blood flow and pressure. On one hand, increased pressure/stretch for a prolonged time can cause structural changes in vessel wall; on the other hand, lack of pressure/stretch can promote a phenotype shift. READ MORE

  6. 4. Effects of the host defense peptide LL-37 on human cells : Immunomodulation and cytotoxicity

    Author : Sara Bodahl; Kärlfysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LL-37; Host defense peptides; Cathelicidin; Inflammation; Cytotoxicity; TLR3; Poly I:C;

    Abstract : The human host defense peptide LL-37 has an essential role in the first line of defense against invading pathogens. This cathelicidin is mainly produced by immune cells and epithelial cells aligning the mucosal areas and is normally upregulated upon infection and inflammation. READ MORE

  7. 5. Identification and characterization of new mechanisms in cardiovascular estrogen signaling

    Author : Anders Holm; Kärlfysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endothelial cells; vascular smooth muscle cells; estrogen; GPR30 GPER1; inflammation; calcium; neovascularization; microtubule;

    Abstract : Women before menopause are protected from cardiovascular disease compared to age-matched men through mechanisms associated with the female sex hormone estrogen. There are three known estrogen receptors named ERα, ERβ and GPR30/GPER1, which are all three receptors are expressed in the cardiovascular system. READ MORE