Search for dissertations about: "K-Cl cotransporter"
Found 4 swedish dissertations containing the words K-Cl cotransporter.
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1. Applying the Pump and Leak Hypothesis. An experimental and theoretical investigation of the principles of ion regulation and excitability in the crustacean stretch receptor neuron
Abstract : An invertebrate nerve cell preparation, the lobster stretch receptor neuron, was investigated with respect to maintenance of its resting voltage, intracellular ion concentrations and excitability using voltage clamp technique and ion-selective microelectrodes. It was found that the resting voltage (-65 mV) of microelectrode impaled cells is caused by (a) a homogenous population of K+ channels which we denoted as leak channels (b) an electrogenic and voltage-dependent Na-K pump current and (c) an inward microelectrode-induced "impalement" current carried mainly by Na+. READ MORE
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2. Characterization of cochlear degeneration in the inner ear of the German waltzing guinea pig : a morphological, cellular, and molecular study
Abstract : The German waltzing guinea pig is a new strain of animals with yet unknown gene mutation(s) displaying recessively inherited cochleovestibular impairment. The homozygous animals (gw/gw) are deaf already at birth and display Wpical waltzing behavior throughout life. READ MORE
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3. Cytoskeleton-interacting proteins in brainstem development : roles of KCC2 and Vangl2
Abstract : The brainstem is the most evolutionary conserved division of the brain. It develops from the hindbrain and midbrain regions of the neural tube and forms neural networks that regulate vital functions of the body. One of the most critical roles is to generate respiratory rhythm for the regulation of oxygen, carbon dioxide and pH levels. READ MORE
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4. Chloride Homeostasis in Central Neurons
Abstract : The overall aim of the present thesis is to clarify the control of intracellular chloride homeostasis in central neurons, because of the critical role of chloride ions (Cl–) for neuronal function. Normal function of the central nervous system (CNS) depends on a delicate balance between neuronal excitation and inhibition. READ MORE