Search for dissertations about: "KCNJ5"

Found 2 swedish dissertations containing the word KCNJ5.

  1. 1. Genetic Alterations and Molecular Signatures in Aldosterone Producing Adenomas

    Author : Tobias Åkerström; Peyman Björklund; Tracy Ann Williams; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aldosterone; aldosterone producing adenoma; KCNJ5; ATP1A1; ATP2B3; CACNA1D; CTNNB1;

    Abstract : Primary Aldosteronism (PA) is caused by autonomous overproduction of aldosterone. Aldosterone is necessary for fluid and ion homeostasis. Aberrant overproduction leads to hypertension and cardiovascular damage. READ MORE

  2. 2. Genetic and molecular alterations in aldosterone producing adenomas

    Author : Ravi Kumar Dutta; Peter Söderkvist; Oliver Gimm; Ute Scholl; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Aldosterone producing tumors (APA, also known as Conn tumors) are adrenal tumors that overproduce aldosterone, a hormone that regulates the sodium levels in blood and contributes to blood pressure (BP) regulation. Excessive production of aldosterone causes hypertension and approximately 5-15% of hypertensive patients have hyperaldosteronism, known as primary aldosteronism (PA). READ MORE