Search for dissertations about: "KIF1B"
Found 4 swedish dissertations containing the word KIF1B.
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1. Identification and characterization of candidate genes for neuroblastoma development
Abstract : Neuroblastoma (NB) is the most common tumor during infancy. It arises from undifferentiated cells in the sympathetic nervous system and is characterized by both clinical and genetic heterogeneity. One of the features of NBs with unfavorable outcome is loss on distal chromosome 1p. READ MORE
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2. Genomic characterization of pediatric acute lymphoblastic leukemia by deep sequencing
Abstract : Acute Lymphoblastic Leukemia (ALL) is the most common cancer in children, with close to 200 cases per year in the Nordic countries. Despite recent advances in modern chemotherapies, 20% of the ALL patients experience a relapse. READ MORE
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3. The role of KIF1Bß in neuroblastoma tumour suppression during sympathetic neuron development
Abstract : Neuroblastoma, the most common extra-cranial childhood tumour, is believed to arise from precursor cells of the sympathetic nervous system (neuroblasts). Hemizygous loss of chromosome 1p36 strongly correlates with poor prognosis in neuroblastoma and the 1p36 gene KIF1Bβ has been proposed to be a pathogenic target of this deletion. READ MORE
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4. On genetics and transcriptomics of multiple sclerosis
Abstract : Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system, where both genetic and environmental factors influence one individual's risk of developing the disease. This thesis is focused on genetic and transcriptomic aspects of MS. READ MORE