Search for dissertations about: "KMT2A"

Found 2 swedish dissertations containing the word KMT2A.

2. 1. Genome-wide analysis of KMT2A-rearranged leukemia

   Author : Mattias Pilheden; Avdelningen för klinisk genetik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Leukemia; KMT2A; Characterization;

   Abstract : .... READ MORE

4. 2. Molecular Interrogation and Functional Studies of Acute Leukemia

   Author : Axel Hyrenius Wittsten; Avdelningen för klinisk genetik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute leukemia; KMT2A; Cooperating Lesions; Clonal Relationship; Genomic Profiling; Fusion Genes;

   Abstract : Hematological malignancies are defined by their underlying genetic alterations, many of which are used to diagnose patients to classify them to different risk groups that dictate the therapy given. Recent advances in high-throughput sequencing have highlighted the presence of co-occurring genetic lesions and that they may form distinct genetic clones that evolve throughout disease progression. READ MORE