Search for dissertations about: "Kainic"

Showing result 1 - 5 of 24 swedish dissertations containing the word Kainic.

  2. 1. Anti-Apoptotic Proteins in Nerve Cell Survival and Neurodegeneration

    Author : Laura Korhonen; Marja Jäättelä; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; neuronal cell death; XIAP; RIAP-2; Hippocalcin; Bcl-2; Bcl-X; kainic acid; DRG; estrogen; Neurovetenskap; Neurology; Neurologi; Developmental Neurosciences; medicinsk utvecklings- och neurobiologi;

    Abstract : Apoptosis is a genetically regulated cell death program, which shows distinct morphological characteristics. It takes place during neuronal development and in some neurodegenerative diseases. During apoptosis, the intracellular proteins are degraded by various caspases, cysteine aspartases, which are regulated by pro- and anti-apoptotic signals. READ MORE

  4. 2. Role of intermediate filaments and expression of GFAP and S-100 in astrocytes

    Author : Mei Ding; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Astrocytes; Gliosis; Kainic acid; Transgenic mouse; S-100; GFAP; Vimentin; RVD regulatory volume decrease ; Taurine; Glutamine; Ascorbate; Glucose;

    Abstract : Astrocytes participate in a variety of important physiologic and pathologic processes in the central nervous system (CNS). One of the most remarkable characteristics of astrocytes is their vigorous response to CNS injuries. READ MORE

  5. 3. On the neuropeptide mRNA expression following neuropsychopharmacological treatments

    Author : Olof Zachrisson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cholecystokinin; Excitotoxicity; Electroconvulsive; In situ hybridisation; Kainic acid; Lithium; Manic-depressive illness; Neuropeptide Y; Rat brain; Schizophrenia; Seizure; Somatostatin; Substance P; Tachykinin receptor;

    Abstract : In addition to classical neurotransmitters, an increasing number of neuropeptides have been found in the brain. Although neuropeptides may play important roles especially in higher brain functions such as emotion, mood, memory, and learning, most focus has been directed upon classical neurotransmitters and their receptors. READ MORE

  6. 4. Region-specific expression of the interleukin-1 system in rat brain following endotoxin challenge and excitotoxic neurodegeneration

    Author : Charlotta Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Traditionally, up-regulation and secretion of cytokines are associated with peripheral immune and inflammatory responses. There is now evidence that cytokines also exert various actions in the central nervous system (CNS). READ MORE

  7. 5. Aminergic regulation of neuronal synchrony in the hippocampus

    Author : Richard Andersson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Gamma oscillations (25-80 Hz) are physiological electric activity patterns, prevalent in the brain, which are associated with attention, working memory, sensory perception, long-term memory encoding and recall. Importantly, in mental illnesses featuring cognitive disturbances (such as Schizophrenia or Alzheimer’s disease) there are concomitant disturbances of gamma oscillations. READ MORE