Search for dissertations about: "Kajsa Fritzell"

Found 1 swedish dissertation containing the words Kajsa Fritzell.

2. 1. The ADAR editing enzymes as therapeutic targets

   Author : Kajsa Fritzell; Marie Öhman; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; molekylär biovetenskap; Molecular Bioscience;

   Abstract : Editing by deamination of adenosine to inosine (A-to-I) in double-stranded RNA is a common event in the human transcriptome. Altered levels of the essential ADAR1 activity are associated with disease. Children with mutations in the ADAR1 gene suffer from fatal Aicardi-Goutières syndrome (AGS) characterized by aberrant interferon expression. READ MORE