Search for dissertations about: "Kardiovaskulär Forskning - Immunitet Och Ateroskleros"

Showing result 1 - 5 of 23 swedish dissertations containing the words Kardiovaskulär Forskning - Immunitet Och Ateroskleros.

2. 1. Analysis of Complement Deficiency States. With Focus on Molecular Characterization of C4 and Properdin Deficiency

   Author : Gunilla Nordin Fredrikson; Kardiovaskulär forskning - immunitet och ateroskleros; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mycology; virology; bacteriology; Complement C4; Complement; Complement Screening; Deficiency; Meningococcal Disease; Properdin; Properdin Expression; Microbiology; Sequencing; Mikrobiologi; bakteriologi; virologi; mykologi;

   Abstract : Complement deficiency is associated with an increased risk for invasive infection and immune complex disease. Screening for identification of complement-deficient patients is essential and a new ELISA-based procedure for detection of complement deficiency is described. READ MORE

4. 2. Interleukin 16 in Atherosclerosis and Cardiovascular Disease

   Author : Caitriona Grönberg; Kardiovaskulär forskning - immunitet och ateroskleros; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Interleukin 16 IL-16 ; atherosclerosis; cardiovascular disease; Immune system; cytokine; carotid plaque; ;

   Abstract : Background and aim - The development of clinical manifectations due to an eroded or ruptured atherosclerotic plaque, or occluded vessel, are one of the major causes of death world wide. It has been known for some time that atherosclerosis develops due to retention and modification of LDL particles in the vessel wall and the subsequent triggering of the immune system. READ MORE

5. 3. Lyso-PC and macrophage interplay. Scavenging through the fatty side of atherosclerosis

   Author : Katarina Berg; Kardiovaskulär forskning - immunitet och ateroskleros; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : Atherosclerosis is triggered by LDL entrapment in the vessel wall. Oxidation and enzymatic processing of LDL give rise to inflammatory mediators such as lyso-PC. These inflammatory mediators attract monocytes into the vessel wall where they differentiate into macrophages. The macrophages adopt different phenotypes depending on the environment. READ MORE

6. 4. Calcium channel activity and force regulation in smooth muscle: Effects of polyamines and growth stimulation

   Author : Maria Gomez; Kardiovaskulär forskning - immunitet och ateroskleros; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; verapamil; tissue culture; portal vein; patch-clamp; calcium; spermidine; spermine; polyamines; excitation-contraction; smooth muscle; calcium channel; ionomycin.; Physiology; Fysiologi;

   Abstract : The initial signal for contraction in smooth muscle is an increase in [Ca2+]i. Ca2+ ions can either enter the cytosol from the extracellular medium or be released from intracellular stores. Voltage-operated Ca2+ channels (VOC) play a dominant role in the activation of smooth muscle contraction. READ MORE

7. 5. Intracellular lipids and inflammatory activity in macrophage foam cells

   Author : Jenny Persson; Kardiovaskulär forskning - immunitet och ateroskleros; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Cardiovascular system; lipid droplet; cytokine; inflammation; adipophilin; perilipin; atherosclerosis; Macrophage; foam cell;

   Abstract : Cardiovascular disease (CVD) is characterized by lipid accumulation and inflammation in arteries. The disease starts early in life with migration of monocytes into the arterial wall where they engulf entrapped lipoproteins and become macrophage foam cell. READ MORE