Search for dissertations about: "Karin Thorsheim"

Found 1 swedish dissertation containing the words Karin Thorsheim.

2. 1. Exploration of the active site of β4GalT7 – Synthesis of substrates and inhibitors

   Author : Karin Thorsheim; Centrum för analys och syntes; []
   Keywords : Xylosides; β4GalT7; β-1; 4-galactosyltransferase 7; glycosaminoglycan; synthesis;

   Abstract : β-1,4-Galactosyltransferase 7 (β4GalT7) is a key enzyme in the biosynthesis of proteoglycans (PGs) and glycosaminoglycan (GAG) chains, which are important macromolecules involved in many biological processes such as cell growth and cell signaling as well as in cancer pathobiology and viral and bacterial infections. Despite its pivotal role, much is still unknown regarding the specific structure of GAGs and how the structure affects its functions. READ MORE