Search for dissertations about: "Karl Hult"
Showing result 1 - 5 of 15 swedish dissertations containing the words Karl Hult.
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1. Exploiting enzyme promiscuity for rational design
Abstract : Enzymes are today well recognized in various industrial applications, being an important component in detergents, and catalysts in the production of agrochemicals, foods, pharmaceuticals, and fine chemicals. Their large use is mainly due to their high selectivity and environmental advantage, compared to traditional catalysts. READ MORE
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2. Lipase-Catalyzed Syntheses of Telechelic Polyesters
Abstract : Telechelic polyesters have successfully been synthesized with lipase-catalyzed polymerization. The produced telechelics had a high degree of difunctionalization, high purity (requiring little or no workup) and controlled degree of polymerization. The syntheses were performed in one-pot one-step reaction systems. READ MORE
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3. Enzyme substrate solvent interactions : a case study on serine hydrolases
Abstract : Reaction rates and selectivities were measured for transacylation of fatty acid esters in solvents catalysed by Candida antarctica lipase B and by cutinase from Humicola insolens. With these enzymes classical water-based enzymology can be expanded to many different solvents allowing large variations in interaction energies between the enzymes, the substrates and the surrounding. READ MORE
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4. Molecular modelling - understanding and prediction of enzyme selectivity
Abstract : Molecular modelling strategies for evaluation of enzyme selectivity wereinvestigated with a focus on principles of how molecular interactionscould be evaluated to provide information about selectivity. Althoughmolecular modelling provides tools for evaluation of geometrical andenergy features of molecular systems, no general strategies for evaluationof enzyme selectivity exist. READ MORE
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5. Enzyme selectivity as a tool in analytical chemistry
Abstract : Enzymes are useful tools as specific analytical reagents. Two different analysis methods were developed for use in the separate fields of protein science and organic synthesis. Both methods rely on the substrate specificity of enzymes. Enzyme catalysis and substrate specificity is described and put in context with each of the two developed methods. READ MORE