Search for dissertations about: "Katarzyna Palica"

Found 2 swedish dissertations containing the words Katarzyna Palica.

  1. 1. Development of phosphorus-containing metallo-β-lactamase inhibitors : Synthesis and binding studies by solution NMR and molecular docking

    Author : Katarzyna Palica; Máté Erdélyi; Christopher J. Schofield; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MBL inhibitors; antibiotic resistance; metallo-β-lactamases; NMR spectroscopy; Medicinal Chemistry; Läkemedelskemi;

    Abstract : The rapidly growing bacterial resistance development is turning into one of the main challenges of the 21st century. Our antibiotics are becoming ineffective for the treatment of bacterial infections, and without successful action, simple infections, such as pneumonia or Septicemia, will soon carry a highly probable mortal prognosis. READ MORE

  2. 2. Phosphonamidates as potential NDM-1 inhibitors

    Author : Katarzyna Palica; Mate Erdelyi; Lindon Moodie; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : WHO’s recent reports indicate that the rapidly growing resistance of bacteria became one of the biggest problems of the XXI century. The most powerful human counter weapon, antibiotics, starts to become ineffective for the treatment of bacterial infections. READ MORE