Search for dissertations about: "Keratinocytes tissue engineering"

Showing result 1 - 5 of 7 swedish dissertations containing the words Keratinocytes tissue engineering.

  2. 1. Keratinocytes in tissue engineering of human skin: invitro and in vivo studies

    Author : Camilla Fredriksson; Gunnar Kratz; Fredrik Huss; Xiao-Feng Sun; Bengt Gerdin; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Keratinocytes tissue engineering; Plastic surgery; Plastikkirurgi;

    Abstract : Full thickness wounds, such as deep burns, need restoration of both the dermal and epidermal layers of the skin. In normal wound healing, re-epithelialization occurs by migration and proliferation of keratinocytes from the wound edges and by differentiation of stem cells from remaining hair follicles. READ MORE

  4. 2. Disease-causing Keratin Mutations and Cytoskeletal Dysfunction in Human Skin : In vitro Models and new Pharmacologic Strategies for Treating Epidermolytic Genodermatoses

    Author : Jean Christopher Chamcheu; Anders Vahlquist; Hans Törmä; Harshad Navsaria; Marie Virtanen; Torbjörn Egelrud; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; epidermolysis bullosa simplex; epidermolytic ichthyosis; genodermatoses; keratin; keratin mutation; keratinocytes; gene therapy; pharmacological therapy; immortalization; gene regulation; trimethylamine N-oxide TMAO ; sodium 4-phenylbutyrate 4-PBA ; tissue engineering; cell culture; heat shock proteins; MAP kinases; Dermatology and venerology; Dermatologi och venerologi; Dermatologi och venereologi; Dermatology and Venerology;

    Abstract : Epidermolysis bullosa simplex (EBS) and epidermolytic ichthyosis (EI) are rare skin fragility diseases characterized by intra-epidermal blistering due to autosomal dominant-negative mutations in basal (KRT5 or KRT14) and suprabasal (KRT1 or KRT10) keratin genes,  respectively. Despite vast knowledge in the disease pathogenesis, the pathomechanisms are not fully understood, and no effective remedies exist. READ MORE

  5. 3. Recombinant spider silk for biomedical applications - from functionalizing surfaces of synthetic materials to in vitro modelling of tissues

    Author : Christos Panagiotis Tasiopoulos; My Hedhammar; Antonella Motta; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; recombinant spider silk; surface functionalization; in vitro tissue models; membrane-based models; barrier tissues; cell co-culture; tissue engineering; Bioteknologi; Biotechnology;

    Abstract : Spider silk is a natural protein-based material known for its medicinal use and remarkable mechanical properties. Structures made thereof are both strong and elastic and have been shown to be favorable matrices for tissue engineering. READ MORE

  6. 4. degradable electroactive polymers: Synthesis, Macromolecular architecture and scaffold design

    Author : Baolin Guo; Ann-Christine Albertsson; Patric Jannasch; KTH; []
    Keywords : Poly lactide ; poly ε-caprolactone ; ring-opening polymerization; carboxyl-capped aniline trimer; carboxyl-capped aniline pentamer; phenyl amino-capped aniline tetramer; coupling reaction; DCC DMAP system; degradability; electroactivity; conductivity; macromolecular architecture; chitosan; hydrogel; block copolymer; functionalization; oxidative coupling reaction; self-assembly; toxicity; tubular porous scaffold; neural tissue engineering.;

    Abstract : Electrically conducting polymers induce specific cellular responses at the molecular level. One of the crucial limitations of the use of conducting polymers in tissue engineering is their inability to degrade. READ MORE

  7. 5. In vitro and in vivo studies on biodegradable matrices for autotransplantation

    Author : Carl-Johan Gustafson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : In vitro; in vivo; dermis; matrix; autotransplantation; culture; keratinocytes; urothelium; tissue engineering; PUUR; macroporous spheres ; guided tissue regeneration;

    Abstract : Tissue engineering (TE), one of the most rapidly growing fields of life science, is an interdisciplinary area in which technical, biological and medical expertise co-fertilize on another with the ultimate aim of restoring, maintaining or improving tissues and/or organs. This purpose links TE closely to research concerning reconstructive plastic surgery. READ MORE