Search for dissertations about: "Ketone reduction"
Showing result 1 - 5 of 18 swedish dissertations containing the words Ketone reduction.
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1. Bioreduction of Carbonyl Compounds to Chiral Alcohols by Whole Yeast Cells: Process Optimisation, Strain Design and Non-Conventional Yeast Screening
Abstract : Chiral building blocks are needed for the production of drugs and fine chemicals, which requires the use of several synthetic routes to produce a specific enantiomer of interest. One promising approach to introduce chirality into molecules is the stereo-selective whole cell bioreduction of carbonyl compounds or ketones to the corresponding chiral alcohols. READ MORE
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2. Ruthenium-Catalyzed Asymmetric Transfer Hydrogenation
Abstract : This thesis covers the development of two new methods for the asymmetric reduction of ketones and ketone intermediates. The protocols developed are based on the use of a ruthenium pseudo-dipeptide catalyst that previously has been shown to be efficient and selective in the asymmetric reduction of carbonyl compounds. READ MORE
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3. Palladium-catalyzed lignin valorization : Towards a lignin-based biorefinery
Abstract : The work described in this thesis focuses on the cleavage of the β-O-4′ bond, which is the most abundant interunit linkage in the lignin polymer.In the first part, three methods based on palladium catalysis have been developed and their applicability has been verified using lignin model compounds. READ MORE
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4. Hydrogenation, Transfer Hydrogenation and Hydrogen Transfer Reactions Catalyzed by Iridium Complexes
Abstract : The work described in this thesis is focused on the development of new bidentate iridium complexes and their applications in the asymmetric reduction of olefins, ketones and imines. Three new types of iridium complexes were synthesized, which included pyridine derived chiral N,P-iridium complexes, achiral NHC complexes and chiral NHC-phosphine complexes. READ MORE
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5. Studies towards ß-turn mimetics, synthesis of kedarosamine from threonine, and synthesis of glycopeptides from mucins and gp120
Abstract : The secondary structure of proteins is crucial for proper function of the protein in biological systems. Peptide T, an octapeptide from the envelope glycoprotein gp120 of the HIV virus, has previously been shown to be responsible for binding to the CD4 receptor on T helper/inducer lymphocytes. READ MORE