Search for dissertations about: "Ki-67"

Showing result 1 - 5 of 82 swedish dissertations containing the word Ki-67.

2. 1. Prognostic factors in soft tissue sarcoma. Tissue microarray for immunostaining, the importance of whole-tumor sections and time-dependence

   Author : Jacob Engellau; Bröstcancer-genetik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; growth pattern; time-dependence; P-glycoprotein Pgp ; CD44; β-catenin; cyclin A; bcl-2; p53; Ki-67; immunohistochemistry IHC ; whole-tumor sections; tissue microarray TMA ; Soft tissue sarcoma; prognostic factors; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

   Abstract : In adult soft tissue sarcoma (STS) of the extremities and trunk wall, improved prognostic factors are needed to identify patients at high-risk for metastasis. Various factors are included in the many prognostic systems currently in use and the prognostic value of immunohistochemical (IHC) expression of biological markers is unclear. READ MORE

4. 2. Aggressive lymphoma

   Author : Mats Jerkeman; Bröstcancer-genetik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytology; BCL6 rearr; 1q21-23; cytogenetics; histopathology; P-glycoprotein; p53; BCL2; Ki-67; immunohistochemistry; proliferation; dose intensity; health-related quality of life; International Prognostic Index; prognostic factors; aggressive lymphoma; chemotherapy; patologisk anatomi; Patologi allmän ; pathological anatomy; General pathology; cancer; onkologi; Cytologi; cancerology; oncology;

   Abstract : Aggressive lymphoma is a rapidly growing tumour of lymphocyte origin, potentially curable with chemotherapy. In a trial by the Nordic Lymphoma Group, 405 patients with aggressive lymphoma were included, and randomised to receive either the standard chemotherapy regimen, CHOP, or a weekly multidrug regimen, MACOP-B. READ MORE

5. 3. Cyclin A and cyclin E as prognostic factors in early breast cancer

   Author : Cecilia Ahlin; Marie-Louise Fjällskog; Carl Blomqvist; Göran Landberg; Uppsala universitet; []
   Keywords : Oncology; breast cancer; chemotherapy; cyclin A; cyclin E; aberrant cyclin E; Ki-67; TMA; Onkologi;

   Abstract : Breast cancer is one of the most common malignancies in women. Due to early detection and the use of screening programs approximately 60% of all new cases lack lymph node involvement. Today, a substantial proportion of these women will be offered adjuvant systemic chemotherapy. READ MORE

6. 4. Diffuse large B-cell lymphoma – studies on immunohistochemical and clinical prognostic factors

   Author : Sverker Hasselblom; Göteborgs universitet; []
   Keywords : DLBCL; prognosis; sex; population-based; apoptosis; Ki-67; CTLs; TIA-1; FOXP3; bcl-2; GCB; p-AKT;

   Abstract : DLBCL, the most common lymphoma entity, is a potentially curable but heterogeneous disease. Most studies concerning therapy and prognostic factors have been performed on selected patient materials. It is important to identify immunohistochemical biomarkers which could add prognostic information to clinical factors. READ MORE

7. 5. Endosonography and pretreatment tumor profiling - from sampling, staining, to sequencing

   Author : Per Hedenström; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endosonography; fine-needle biopsy; pancreatic neoplasms; gastrointestinal stromal tumors; KIT; PDGFRA; Ki-67; imatinib; neoadjuvant therapy;

   Abstract : Background and aims: Endosonography-guided fine needle aspiration (EUS-FNA) is imperfect in diagnosing solid pancreatic lesions (SPL) and subepithelial lesions (SEL) including gastrointestinal stromal tumors (GIST). In GISTs, imatinib therapy is effective only in variants of oncogenes KIT and PDGFRA. READ MORE