Search for dissertations about: "Klara Martinsson"

Found 2 swedish dissertations containing the words Klara Martinsson.

  1. 1. Fcγ-receptors in systemic autoimmune conditions : lessons from murine mercury-induced autoimmunity

    Author : Klara Martinsson; Per Hultman; Karin Cederbrant; Johan Rönnelid; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : In this thesis we investigated the role of activating (FcγRI, FcγRIII) and inhibitory (FcγRIIB) Fcγ-receptors on systemic autoimmunity using two mouse strains, DBA/1 (H-2q) and BALB/c mice (H-2d), susceptible to induction of autoimmunity by mercury (Hg).Fc-receptors for IgG (FcγR) link cellular and humoral immune responses, control the balance between activating and inhibitory immune responses and are important in the development of several autoimmune diseases. READ MORE

  2. 2. Secretory Autoantibodies in Rheumatoid Arthritis

    Author : Karin Roos Ljungberg; Alf Kastbom; Anna Svärd; Klara Martinsson; Jonas Wetterö; Per-Johan Jakobsson; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; Secretory autoantibodies; Immunoglobulins; Anti-citrullinated protein antibodies; ACPA; Mucosal immunity;

    Abstract : Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease in which autoantibodies, such as anti-citrullinated protein antibodies (ACPA), can be detected in the serum of patients. Autoantibodies may appear in the circulation years before clinical signs of joint inflammation occur, indicating that early immunological pathogenetic steps take place outside of the joints. READ MORE