Search for dissertations about: "Klinisk kemi"
Showing result 1 - 5 of 243 swedish dissertations containing the words Klinisk kemi.
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1. Pilicides and Curlicides : Design, synthesis, and evaluation of novel antibacterial agents targeting bacterial virulence
Abstract : New strategies are needed to counter the growing problem of bacterial resistance to antibiotics. One such strategy is to design compounds that target bacterial virulence, which could work separately or in concert with conventional bacteriostatic or bactericidal antibiotics. READ MORE
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2. Controlled release gel formulations and preclinical screening of drug candidates
Abstract : Simple gel formulations may be applied to enhance the systemic and local exposure of potential compounds. The aim of this thesis is the development and characterization of controlled release formulations based on thermo-reversible poloxamer gels, which are suitable for novel drug delivery applications. READ MORE
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3. Biomarkers for Better Understanding of the Pathophysiology and Treatment of Chronic Pain : Investigations of Human Biofluids
Abstract : Chronic pain affects 20 % of the global population, causes suffering, is difficult to treat, and constitutes a large economic burden for society. So far, the characterization of molecular mechanisms of chronic pain-like behaviors in animal models has not translated into effective treatments. READ MORE
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4. Rational design and synthesis of protease inhibitors : targeting HIV-1, Malaria Plm I and II and Hepatitis C virus NS3 proteases
Abstract : .... READ MORE
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5. Tailoring Fluorescent Probes for Organelle-Specific Imaging and Sensing
Abstract : Exploring and visualizing biological and pathological processes in living cells are useful for both fundamental research and applications. An understanding on the molecular level for these processes with focus on tracking biomarkers, collecting information about their surroundings, and uncovering essential molecular pathways and functions in live cells are of vital interest for cell biological study and clinical diagnosis application. READ MORE
