Search for dissertations about: "Knut Stokkeland"

Found 1 swedish dissertation containing the words Knut Stokkeland.

  1. 1. Studies on alcoholic liver disease

    Author : Knut Stokkeland; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; alcohol cirrhosis; cytochromes; autoantibodies; mortality; morbidity; prognosis; epidemiology; esophageal varices; lifetime drinking; lifetime alcohol intake;

    Abstract : The overall aim of this thesis was to explore the impact of alcoholic cirrhosis in Sweden, and the relation between drinking patterns and beverage types and alcoholic cirrhosis, and to evaluate the possible role of autoantibodies in the pathogenesis of alcohol related liver disease. We found that rats had appearance of IgG against rat CYP3A 1 and CYP2E 1 during chronic ethanol feeding We found that patients had reactivity against CYP3A4 and CYP2E I in about 20 to 30% and 10 to 20% of the alcoholic sera. READ MORE