Search for dissertations about: "Konstantin Galichanin"

Found 3 swedish dissertations containing the words Konstantin Galichanin.

  2. 1. Ultraviolet radiation cataract

    Author : Konstantin Galichanin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : lens;

    Abstract : Cataract is the leading cause of blindness in the world. Epidemiological and experimental evidence supports a link between mid-range ultraviolet radiation (UVR-B) exposure and the development of cataract. READ MORE

  4. 2. Caspase-3 in lens epithelium

    Author : Nooshin Talebizadeh; Per Söderberg; Finn Hallböök; Konstantin Galichanin; Michael Wormstone; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ultraviolet radiation; caspase-3; lens; cataract; apoptosis; Immunohistochemistry; spatial distribution; time evolution; modelling; automatic analysis; cell counting; image analysis.; Ophtalmology; Oftalmiatrik;

    Abstract : Purpose: To model the time evolution of active caspase-3 protein expression in a healthy lens, and in a lens exposed to UVR-300 nm (UVR-B). To develop an automated method to classify the fluorescent signal of biomarkers in the lens epithelial cells.Methods: Six-week old Sprague-Dawley rats were used. READ MORE

  5. 3. Damage mechanisms for near-infrared radiation induced cataract

    Author : Zhaohua Yu; Per Söderberg; Konstantin Galichanin; Masami Kojima; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; infrared radiation; photochemical; thermal; forward light scattering; lens; cataract; temperature; Arrhenius equation; heat diffusion;

    Abstract : Purpose: 1) To estimate the threshold dose and the time evolution for cataract induction by near infrared radiation (IRR) in seconds exposure time domain; 2) to determine the ocular temperature development during the threshold exposure; 3) to investigate if near IRR induces cumulative lens damage considering irradiance exposure time reciprocity; 4) to experimentally estimate the temperature in the lens indirectly from the measurement of temperature-induced light scattering increase.Methods: Before exposure, 6-weeks-old albino rats were anesthetized and the pupils of both eyes were dilated. READ MORE